Estimation of Some Biochemical Parameters of Elderly Women

Intisar Ghanim Taha; Eman Salem Mahmoud; Mahasin Aziz M. Hasan

المؤلفون

Intisar Ghanim Taha Basic Science Department, College of Basic Education, University of Mosul, Mosul, Iraq مؤلف
Eman Salem Mahmoud Basic Science Department, College of Dentistry, University of Mosul, Mosul, Iraq مؤلف
Mahasin Aziz M. Hasan Ibin Al Atheer Hospital, chemistry Lab., Mosul, Iraq مؤلف

الكلمات المفتاحية:

Leptin، Tumor necrosis factor (TNF-α)، Interleukin 6 (IL-6)، Diponectin، C-reactive protein (CRP)

الملخص

This paper aims to find adiponectin, leptin, inflammatory markers (IL-6, CRP, and TNF-α), calcium, and vitamin (D) in (healthy-looking) older people. This study recruited 82 healthy women between the ages of 68 and 90 who volunteered to participate between July 2020 and December 2021. Excluded were patients with acute cardiac failure, autoimmune illness, infectious disease, malignancy, and liver dysfunction. A total of 60 healthy females, ages 22 to 38, made up the control group. The elderly women showed considerably greater levels of leptin, tumor necrosis factor-alpha, interleukin-6, and CRP in contrast to the control group, while their levels of adiponectin had significantly decreased. Vitamin D and calcium rates were also drastically reduced among the elder women than in females who were used as a comparison group. For this study, researchers examined the role of inflammatory mediators as biomarkers for frailty detection in older persons, focusing on the influence of ageing on pro/anti-inflammatory adipokines. The concentration of these indicators in adults and the elderly was therefore compared to achieve this goal.