Hypothyroidism and Its Association with Serum Cholesterol and Triglyceride Levels in Children

Authors

  • Asma Mohammed Gliwan Department of Chemistry, Faculty of Science, University of Misurata, Misurata, Libya Author
  • Nasma Ahmed Al-Masrati Department of Chemistry, Faculty of Science, University of Misurata, Misurata, Libya Author
  • Haifa Abdel Salam Ishkab Department of Chemistry, Faculty of Science, University of Misurata, Misurata, Libya Author

Keywords:

Hypothyroidism, Thyroid-Stimulating Hormone (TSH), Thyroxine (T4), Total Cholesterol, Triglycerides (TG), Dyslipidemia, Children

Abstract

This study aimed to analyze the relationship between hypothyroidism and elevated levels of total cholesterol and triglycerides in children. The sample included 40 patients (21 males and 19 females) aged between one month and 16 years. The results demonstrated a strong positive correlation between elevated thyroid-stimulating hormone (TSH) levels and increased total cholesterol (R = 0.634, p = 0.005) as well as triglyceride levels (R = 0.838, p = 0.000). Conversely, thyroxine (T4) showed a significant inverse correlation with these parameters (R = −0.740 for cholesterol and R = − 0.831 for triglycerides). These findings indicate that hypothyroidism adversely affects lipid metabolism, thereby increasing the risk of cardiovascular diseases in children.

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Published

2026-02-08

Issue

Volume 4, No. 1, 2026

Section

Applied Sciences Theme

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Asma Mohammed Gliwan, Nasma Ahmed Al-Masrati, & Haifa Abdel Salam Ishkab. (2026). Hypothyroidism and Its Association with Serum Cholesterol and Triglyceride Levels in Children. Afro-Asian Journal of Scientific Research (AAJSR), 4(1), 211-216. https://aajsr.com/index.php/aajsr/article/view/787